Hypericum perforatum Overview Page
Permission granted to use by USDA with photo taken by Peggy
Greb
Common NameSt. John's Wort | Taxonomic ClassificationHypericaceae family |
Drug Uses
Hypericum perforatum had been known to have many medicinal effects. Three compounds: hypericin, hyperforin, and quercetin are currently being used in clinical tests and able to show a variety of effects. Some of these effects are: antiretroviral, anticancer, anti-depressive, anti-autoimmune, anticancer. These three chemicals are characterized in three separate class of chemical, hypericin is a dianthrone, hyperforin is an acyl-phloroglucinol, and quercetin is a flavonoid.
| Chemical Structure: Hypericin | Clinical Trials | Major Metabolites |
|---|---|---|
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Enzyme Information
| Enzyme Name | EC No | Genbank Accession | GI No |
|---|---|---|---|
| Phenolic oxidative coupling protein | N/A | AAN65449.1 | 25136299 |
| Octaketide synthase | N/A | ACF37207.1 | 194272335 |
| Polyketide synthase | N/A | ABP98923.1 | 145926649 |
| Polyketide synthase | N/A | ABP98922.1 | 145926640 |
Entries in Genbank
| dbEST/(Kb) | dbGSS/(Kb) | dbPLN/(Kb) | dbHTG/(Kb) | Total Entriesa/(Kb) |
|---|---|---|---|---|
| 3 (0.683kb) | 0 (0kb) | 47 (37.3kb) | 0 (0kb) | 50 (38.0kb) |
aThe Total Entries column is the sum of the entries from the dbEST, dbGSS, dbPLN, and dbHTG columns. Data retrieved from NCBI on May 14 2010.
Transcript Assemblies
Cloned Genes
- HpPKS2
Pubmed Records
- 744 records
See all Hypericum perforatum papers within last Week, Month or Year.